{"id":1037,"date":"2022-11-28T17:57:43","date_gmt":"2022-11-28T16:57:43","guid":{"rendered":"https:\/\/farmacognosia.unimi.it\/scientific-publications\/"},"modified":"2025-10-28T13:40:30","modified_gmt":"2025-10-28T12:40:30","slug":"scientific-publications","status":"publish","type":"page","link":"https:\/\/farmacognosia.unimi.it\/en\/scientific-publications\/","title":{"rendered":"Scientific publications"},"content":{"rendered":"\n<div class=\"wp-block-cover is-light\"><span aria-hidden=\"true\" class=\"wp-block-cover__background has-white-background-color has-background-dim-30 has-background-dim\"><\/span><img loading=\"lazy\" decoding=\"async\" width=\"720\" height=\"405\" class=\"wp-block-cover__image-background wp-image-615\" alt=\"\" src=\"https:\/\/farmacognosia.unimi.it\/wp-content\/uploads\/sites\/39\/2023\/04\/Journals.jpg\" data-object-fit=\"cover\" srcset=\"https:\/\/farmacognosia.unimi.it\/wp-content\/uploads\/sites\/39\/2023\/04\/Journals.jpg 720w, https:\/\/farmacognosia.unimi.it\/wp-content\/uploads\/sites\/39\/2023\/04\/Journals-600x338.jpg 600w\" sizes=\"(max-width: 720px) 100vw, 720px\" \/><div class=\"wp-block-cover__inner-container is-layout-flow wp-block-cover-is-layout-flow\">\n<p class=\"has-text-align-center has-black-color has-white-background-color has-text-color has-background has-medium-font-size\">A selection of the most recent publications in <strong>international scientific journals<\/strong> with impact-factor relating to the <strong>research work<\/strong> of the Laboratory of Pharmacognosy and those carried out in <strong>collaboration<\/strong> with other research groups<\/p>\n<\/div><\/div>\n\n<h2 class=\"wp-block-heading\"><strong>2025<\/strong><\/h2>\n\n<p>Martinelli G, Maranta N, Nicotra G, Vicentini SF, Bruno B, Baron G, Di Lorenzo C, Moheb El Haddad S, Fumagalli M, Pozzoli C, Sangiovanni E, Aldini G, Dell\u2019Agli M, Piazza S. <em>Cistus x incanus <\/em>L. extract as a complex polyphenolic blend with retained anti-adhesive and anti-inflammatory properties in a model of E. coli-induced UTI following simulated digestion. <em>J Ethnopharmacol.<\/em> 2025;120786. doi: <a href=\"https:\/\/doi.org\/10.1016\/j.jep.2025.120786\">https:\/\/doi.org\/10.1016\/j.jep.2025.120786<\/a>  <\/p>\n\n<p>Maranta N, Martinelli G, Fumagalli M, Pozzoli C, Sonzogni E, Rossini N, Ciriello U, Paladino G, Dell&#8217;Agli M, Piazza S, Sangiovanni E. Efficacy of non-psychotropic <em>Cannabis sativa<\/em> L. standardized extracts in a model of intestinal inflammation. <em>J Cannabis Res.<\/em> 2025 Oct 6;7(1):74. doi: <a href=\"https:\/\/doi.org\/10.1186\/s42238-025-00335-2\">https:\/\/doi.org\/10.1186\/s42238-025-00335-2<\/a>  <\/p>\n\n<p>Magnavacca A, Martinelli G, Maranta N, Pozzoli C, Fumagalli M, Beretta G, Piazza S, Dell\u2019Agli M, Sangiovanni E. Assessment of the Polyphenolic Profile and Beneficial Effects of Red and Green Propolis in Skin Inflammatory Conditions and Oxidative Stress. <em>Biomedicines<\/em>. 2025; 13(9):2229.  <a href=\"https:\/\/doi.org\/10.3390\/biomedicines13092229\">https:\/\/doi.org\/10.3390\/biomedicines13092229<\/a><\/p>\n\n<p>Scarpato S, Venturi D, Palma Esposito F, Mangano MC, Sar\u00e0 G, Margiotta F, Pagano E, Miraglia M, Sangiovanni E, Garcia-Gil M, Di Cesare Mannelli L, Ghelardini C, Dell&#8217;Agli M, Izzo AA, Nieri P, de Pascale D, Della Sala G. Bioactivity Assessment and Untargeted Metabolomics of the Mediterranean Sea Pen <em>Pennatula phosphorea<\/em>. <em>Mar Drugs.<\/em> 2025 May 21;23(5):218. <a href=\"https:\/\/www.mdpi.com\/1660-3397\/23\/5\/218\">doi: 10.3390\/md23050218. <\/a> <\/p>\n\n<p>Martinelli G, Piazza S, Fumagalli M, Maranta N, Pozzoli C, Sonzogni E, Moheb El Haddad S, Vrhovsek U, Mattivi F, Sangiovanni E, De Fabiani E, Dell&#8217;Agli M. Investigating ellagitannins from strawberry (<em>Fragaria<\/em>\u00d7 <em>ananassa<\/em> Duch.) as a new strategy to counteract <em>H. pylori<\/em> infection and inflammation. <em>Food Funct.<\/em> 2025 Jun 16;16(12):5049-5058. doi: <a href=\"https:\/\/doi.org\/10.1039\/d5fo01022e\">10.1039\/d5fo01022e. <\/a>  <\/p>\n\n<p>Fumagalli M, Martinelli G, Paladino G, Rossini N, Ciriello U, Nicolaci V, Maranta N, Pozzoli C, El Haddad SM, Sonzogni E, et al. Beyond Cannabidiol: The Contribution of <em>Cannabis sativa<\/em> Phytocomplex to Skin Anti-Inflammatory Activity in Human Skin Keratinocytes. <em>Pharmaceuticals<\/em>. 2025; 18(5):647.   <a href=\"https:\/\/doi.org\/10.3390\/ph18050647\">https:\/\/doi.org\/10.3390\/ph18050647<\/a><\/p>\n\n<p>Vesci L, Martinelli G, Liu Y, Tagliavento L, Dell&#8217;Agli M, Wu Y, Soldi S, Sagheddu V, Piazza S, Sangiovanni E, Meneguzzo F. The New Phytocomplex AL0042 Extracted from Red Orange By-Products Inhibits the Minimal Hepatic Encephalopathy in Mice Induced by Thioacetamide. <em>Biomedicines<\/em>. 2025 Mar 11;13(3):686. <a href=\"https:\/\/doi.org\/10.3390\/biomedicines13030686\">https:\/\/doi.org\/10.3390\/biomedicines13030686<\/a><\/p>\n\n<p>Corinne Bani, Elena Pe\u00f1as, Giovanna Baron, Cristina Mart\u00ednez-Villaluenga, Francesca Mercogliano, Giancarlo Aldini, Stefano Piazza, Chiara Di Lorenzo, Patrizia Restani. Characterization of the phenolic profile and in vitro antioxidant potential of different varieties of common buckwheat (<em>Fagopyrum esculentum<\/em> Moench) and tartary buckwheat (<em>Fagopyrum tataricum<\/em> (L.) Gaertn.). <em>LWT<\/em>, Volume 215, 2025, 117261. <a href=\"https:\/\/doi.org\/10.1016\/j.lwt.2024.117261\" target=\"_blank\" rel=\"noreferrer noopener\">https:\/\/doi.org\/10.1016\/j.lwt.2024.117261<\/a> <\/p>\n\n<hr class=\"wp-block-separator has-alpha-channel-opacity is-style-wide\" \/>\n\n<h2 class=\"wp-block-heading\">2024<\/h2>\n\n<p>Tesoro C, Lelario F, Piscitelli F, Di Capua A, Della Sala P, Montoro P, Bianco G, Acquavia MA, Dell&#8217;Agli M, Piazza S, Ciriello R. <em>Vicia faba<\/em> L. Pod Valves: A By-Product with High Potential as an Adjuvant in the Treatment of Parkinson&#8217;s Disease. <em>Molecules.<\/em> 2024 Aug 21;29(16):3943.  <a href=\"https:\/\/www.mdpi.com\/1420-3049\/29\/16\/3943\">https:\/\/www.mdpi.com\/1420-3049\/29\/16\/3943<\/a><\/p>\n\n<p>Pozzoli C, Martinelli G, Fumagalli M, Di Lorenzo C, Maranta N, Colombo L, Piazza S, Dell\u2019Agli M, Sangiovanni E. <em>Castanea sativa<\/em> Mill. By-Products: Investigation of Potential Anti-Inflammatory Effects in Human Intestinal Epithelial Cells. <g id=\"gid_1\">Molecules<\/g>. 2024; 29(16):3951.   <a href=\"https:\/\/www.mdpi.com\/1420-3049\/29\/16\/3951\">https:\/\/doi.org\/10.3390\/molecules29163951<\/a><\/p>\n\n<p>Sonzogni, E.; Martinelli, G.; Fumagalli, M.; Maranta, N.; Pozzoli, C.; Bani, C.; Marrari, L.A.; Di Lorenzo, C.; Sangiovanni, E.; Dell\u2019Agli, M.; et al. In Vitro Insights into the Dietary Role of Glucoraphanin and Its Metabolite Sulforaphane in Celiac Disease. <em>Nutrients<\/em> 2024,16,2743. <a href=\"https:\/\/www.mdpi.com\/2072-6643\/16\/16\/2743\">https:\/\/www.mdpi.com\/2072-6643\/16\/16\/2743<\/a><\/p>\n\n<p>Maiocchi A, Fumagalli M, Vismara M, Blanco A, Ciriello U, Paladino G, Piazza S, Martinelli G, Fasano V, Dell&#8217;Agli M, Passarella D. Minor Cannabinoids as Inhibitors of Skin Inflammation: Chemical Synthesis and Biological Evaluation. <em>J Nat Prod.<\/em> 2024 Jul 26;87(7):1725-1734. <a href=\"https:\/\/pubs.acs.org\/doi\/10.1021\/acs.jnatprod.4c00212\">https:\/\/pubs.acs.org\/doi\/10.1021\/acs.jnatprod.4c00212<\/a><\/p>\n\n<p>Piazza, S., Bani, C., Colombo, F., Mercogliano, F., Pozzoli, C., Martinelli, G., Petroni, K., Roberto Pilu, S., Sonzogni, E., Fumagalli, M., Sangiovanni, E., Restani, P., Dell\u2019Agli, M., Di Lorenzo, C., Pigmented corn as a gluten-free source of polyphenols with anti-inflammatory and antioxidant properties in CaCo-2 cells, <em>Food Research International<\/em> (2024), doi: <a href=\"https:\/\/doi.org\/10.1016\/j.foodres.2024.114640\" target=\"_blank\" rel=\"noreferrer noopener\">https:\/\/doi.org\/10.1016\/j.foodres.2024.114640<\/a><\/p>\n\n<p>Magnavacca A, Giuliani C, Roda G, Piazza S, Martinelli G, Pozzoli C, Maranta N, Papini A, Bottoni M, Casagni E, et al. <em>Catha edulis <\/em> Leaves: Morphological Characterization and Anti-Inflammatory Properties in an In Vitro Model of Gastritis. <em>Plants<\/em>. 2024; 13(11):1538. <a href=\"https:\/\/doi.org\/10.3390\/plants13111538\" target=\"_blank\" rel=\"noreferrer noopener\">https:\/\/doi.org\/10.3390\/plants13111538<\/a><\/p>\n\n<p>Piazza S, Martinelli G, Maranta N, Pozzoli C, Fumagalli M, Nicolaci V, Sonzogni E, Colombo L, Sangiovanni E, Dell\u2019Agli M. Investigation into the Anti-Acne Effects of <em>Castanea sativa<\/em> Mill Leaf and Its Pure Ellagitannin Castalagin in HaCaT Cells Infected with <em>Cutibacterium acnes<\/em>. <em>International Journal of Molecular Sciences<\/em>. 2024; 25(9):4764. <a href=\"https:\/\/doi.org\/10.3390\/ijms25094764\" target=\"_blank\" rel=\"noreferrer noopener\">https:\/\/doi.org\/10.3390\/ijms25094764<\/a><\/p>\n\n<p>Bottoni, M.; Martinelli, G.; Maranta, N.; Sabato, E.; Milani, F.; Colombo, L.; Colombo, P.S.; Piazza, S.; Sangiovanni, E.; Giuliani, C.; et al. From Primary Data to Ethnopharmacological Investigations on <em>Achillea erba-rotta <\/em>subsp. <em>moschata <\/em>(Wulfen) I.Richardson as a Remedy against Gastric Ailments in Valmalenco (Italy). <em>Plants <\/em>2024, <em>13<\/em>, 539. <a href=\"https:\/\/doi.org\/10.3390\/plants13040539\" target=\"_blank\" rel=\"noreferrer noopener\">https:\/\/doi.org\/10.3390\/plants13040539<\/a><\/p>\n\n<p>Martinelli G, Fumagalli M, Pozzoli C, Nicotra G, Vicentini SF, Maranta N, Sangiovanni E, Dell\u2019Agli M, Piazza S. Exploring In Vitro the Combination of <em>Cistus<\/em> \u00d7 <em>incanus<\/em> L. and <em>Castanea sativa<\/em> Mill. Extracts as Food Supplement Ingredients against <em>H. pylori<\/em> Infection. <em>Foods<\/em>. 2024; 13(1):40. <a href=\"https:\/\/doi.org\/10.3390\/foods13010040\" target=\"_blank\" rel=\"noreferrer noopener\">https:\/\/doi.org\/10.3390\/foods13010040<\/a><\/p>\n\n<hr class=\"wp-block-separator has-alpha-channel-opacity is-style-wide\" \/>\n\n<h2 class=\"wp-block-heading\">2023<\/h2>\n\n<p>Martinelli G, Fumagalli M, Piazza S, Maranta N, Genova F, Sperandeo P, Sangiovanni E, Polissi A, Dell\u2019Agli M, De Fabiani E. Investigating the Molecular Mechanisms Underlying Early Response to Inflammation and <em>Helicobacter pylori<\/em> Infection in Human Gastric Epithelial Cells. <em>International Journal of Molecular Sciences<\/em>. 2023; 24(20):15147. <a href=\"https:\/\/doi.org\/10.3390\/ijms242015147\" target=\"_blank\" rel=\"noreferrer noopener\">https:\/\/doi.org\/10.3390\/ijms242015147<\/a><\/p>\n\n<p>Anastasia Van der Auwera, Laura Peeters, Kenn Foubert, Stefano Piazza, Wim Vanden Berghe, Nina Hermans, Luc Pieters. In Vitro Biotransformation and Anti-inflammatory Activity of Constituents and Metabolites of <em>Filipendula ulmaria<\/em>. <em>Pharmaceutics<\/em>, 15(4):1291, 2023. <a href=\"https:\/\/doi.org\/10.3390\/pharmaceutics15041291\">https:\/\/doi.org\/10.3390\/<\/a><a href=\"https:\/\/doi.org\/10.3390\/pharmaceutics15041291\" target=\"_blank\" rel=\"noreferrer noopener\">pharmaceutics15041291<\/a><\/p>\n\n<p>Tesoro C, Lelario F, Ciriello R, Bianco G, Acquavia MA, Montoro P, Crescenzi MA, Gregori E, Dell&#8217;Agli M, Piazza S, Guerrieri A, Di Capua A. A validated LC-MS\/MS method for quantitative determination of L-dopa in Fagioli di Sarconi beans (<em>Phaseolus\u2009vulgaris<\/em> L.). <em>J Mass Spectrom. <\/em>2023 Jul 3:e4952. <a href=\"https:\/\/analyticalsciencejournals.onlinelibrary.wiley.com\/doi\/10.1002\/jms.4952\">doi: 10.1002\/jms.4952. <\/a> <\/p>\n\n<p>Piazza S, Martinelli G, Fumagalli M, Pozzoli C, Maranta N, Giavarini F, Colombo L, Nicotra G, Vicentini SF, Genova F, De Fabiani E, Sangiovanni E, Dell\u2019Agli M. Ellagitannins from <em>Castanea sativa<\/em> Mill. Leaf Extracts Impair <em>H. pylori<\/em> Viability and Infection-Induced Inflammation in Human Gastric Epithelial Cells. <em>Nutrients<\/em>. 2023; 15(6):1504. <a href=\"https:\/\/doi.org\/10.3390\/nu15061504\" target=\"_blank\" rel=\"noreferrer noopener\">https:\/\/doi.org\/10.3390\/nu15061504<\/a><\/p>\n\n<p>Piazza S, Colombo F, Bani C, Fumagalli M, Vincentini O, Sangiovanni E, Martinelli G, Biella S, Silano M, Restani P, Dell\u2019Agli M, Di Lorenzo C. Evaluation of the Potential Anti-Inflammatory Activity of Black Rice in the Framework of Celiac Disease. <em>Foods<\/em>. 2023; 12(1):63. <a href=\"https:\/\/doi.org\/10.3390\/foods12010063\" target=\"_blank\" rel=\"noreferrer noopener\">https:\/\/doi.org\/10.3390\/foods12010063<\/a><\/p>\n\n<p>Atchan APN, Monthe OC, Tchamgoue AD, Singh Y, Shivashankara ST, Selvi MK, Agbor GA, Magni P, Piazza S, Manjappara UV, Kuiate JR, Dell&#8217;Agli M. Anti-Inflammatory, Antioxidant Activities, and Phytochemical Characterization of Edible Plants Exerting Synergistic Effects in Human Gastric Epithelial Cells. <em>Antioxidants<\/em> (Basel). 2023 Feb 27;12(3):591. doi: <a href=\"https:\/\/www.mdpi.com\/2076-3921\/12\/3\/591\">10.3390\/antiox12030591.<\/a><\/p>\n\n<hr class=\"wp-block-separator has-alpha-channel-opacity is-style-wide\" \/>\n\n<h2 class=\"wp-block-heading\">2022<\/h2>\n\n<p>Piazza S, Fumagalli M, Martinelli G, Pozzoli C, Maranta N, Angarano M, Sangiovanni E, Dell\u2019Agli M. Hydrolyzable Tannins in the Management of Th1, Th2 and Th17 Inflammatory-Related Diseases. <em>Molecules<\/em>. 2022; 27(21):7593. <a href=\"https:\/\/doi.org\/10.3390\/molecules27217593\" target=\"_blank\" rel=\"noreferrer noopener\">https:\/\/doi.org\/10.3390\/molecules27217593<\/a><\/p>\n\n<p>Piazza S, Martinelli G, Magnavacca A, Fumagalli M, Pozzoli C, Terno M, Canilli L, Angarano M, Maranta N, Dell\u2019Agli M, Sangiovanni E. Unveiling the Ability of Witch Hazel (<em>Hamamelis virginiana<\/em> L.) Bark Extract to Impair Keratinocyte Inflammatory Cascade Typical of Atopic Eczema. <em>International Journal of Molecular Sciences.<\/em> 2022; 23(16):9279. <a href=\"https:\/\/doi.org\/10.3390\/ijms23169279\" target=\"_blank\" rel=\"noreferrer noopener\">https:\/\/doi.org\/10.3390\/ijms23169279<\/a><\/p>\n\n<p>Piazza S, Martinelli G, Vrhovsek U, Masuero D, Fumagalli M, Magnavacca A, Pozzoli C, Canilli L, Terno M, Angarano M, Dell\u2019Agli M, Sangiovanni E. Anti-Inflammatory and Anti-Acne Effects of <em>Hamamelis virginiana<\/em> Bark in Human Keratinocytes. <em>Antioxidants<\/em>. 2022; 11(6):1119. <a href=\"https:\/\/doi.org\/10.3390\/antiox11061119\" target=\"_blank\" rel=\"noreferrer noopener\">https:\/\/doi.org\/10.3390\/antiox11061119<\/a><\/p>\n\n<p>Martinelli G, Angarano M, Piazza S, Fumagalli M, Magnavacca A, Pozzoli C, Khalilpour S, Dell\u2019Agli M, Sangiovanni E. The Nutraceutical Properties of Sumac (<em>Rhus coriaria<\/em> L.) against Gastritis: Antibacterial and Anti-Inflammatory Activities in Gastric Epithelial Cells Infected with <em>H. pylor<\/em>i. <em>Nutrients<\/em>. 2022; 14(9):1757. <a href=\"https:\/\/doi.org\/10.3390\/nu14091757\" target=\"_blank\" rel=\"noreferrer noopener\">https:\/\/doi.org\/10.3390\/nu14091757<\/a><\/p>\n\n<p>Melzi G, Marabini L, Marinovich M, Dell&#8217;Agli M, Piazza S, Lombardo G, Donetti E. Photoprotective properties of Vitis vinifera L. leaves extract on UVA-induced damage in human endothelial cells (EA.hy926 cells). Photodermatol Photoimmunol Photomed. 2021 Mar;37(2):171-174. doi: <a href=\"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/phpp.12628\" target=\"_blank\" rel=\"noreferrer noopener\">10.1111\/phpp.12628.<\/a> <\/p>\n\n<p>Magnavacca, A, Sangiovanni, E, Racagni, G, Dell&#8217;Agli, M. The antiviral and immunomodulatory activities of propolis: An update and future perspectives for respiratory diseases. <em>Med Res Rev<\/em>. 2022; 42: 897- 945. <a href=\"https:\/\/doi.org\/10.1002\/med.21866\" target=\"_blank\" rel=\"noreferrer noopener\"><\/a><a href=\"https:\/\/doi.org\/10.1002\/med.21866\">https:\/\/doi.org\/10.1002\/med.21866<\/a><\/p>\n\n<p>Martinelli G, Magnavacca A, Fumagalli M, Dell\u02bcAgli M, Piazza S, Sangiovanni E. Cannabis sativa and Skin Health: Dissecting the Role of Phytocannabinoids. Planta Med. 2022 Jun;88(7):492-506. doi: <a href=\"https:\/\/www.thieme-connect.com\/products\/ejournals\/abstract\/10.1055\/a-1420-5780\" target=\"_blank\" rel=\"noreferrer noopener\">10.1055\/a-1420-5780<\/a>. <\/p>\n\n<p>Nwakiban Atchan AP, Shivashankara ST, Piazza S, Tchamgoue AD, Beretta G, Dell&#8217;Agli M, Magni P, Agbor GA, Kuiat\u00e9 JR, Manjappara UV. Polyphenol-Rich Extracts of Xylopia and Aframomum Species Show Metabolic Benefits by Lowering Hepatic Lipid Accumulation in Diet-Induced Obese Mice. ACS Omega. 2022 Mar 30;7(14):11914-11928. doi: <a href=\"https:\/\/pubs.acs.org\/doi\/10.1021\/acsomega.2c00050\" target=\"_blank\" rel=\"noreferrer noopener\">10.1021\/acsomega.2c00050.<\/a><\/p>\n\n<p>Agbor GA, Dell&#8217;Agli M, Kuiate JR, Ojo O. Editorial: The Role of Medicinal Plants and Natural Products in Modulating Oxidative Stress and Inflammatory Related Disorders. Front Pharmacol. 2022 Jun 24;13:957296. doi: <a href=\"https:\/\/www.frontiersin.org\/articles\/10.3389\/fphar.2022.957296\/full\" target=\"_blank\" rel=\"noreferrer noopener\">10.3389\/fphar.2022.957296.<\/a><\/p>\n\n<p>Mottarlini F, Fumagalli M, Castillo-D\u00edaz F, Piazza S, Targa G, Sangiovanni E, Pacchetti B, Sodergren MH, Dell&#8217;Agli M, Fumagalli F, Caffino L. Single and Repeated Exposure to Cannabidiol Differently Modulate BDNF Expression and Signaling in the Cortico-Striatal Brain Network. Biomedicines. 2022 Aug 1;10(8):1853. doi: <a href=\"https:\/\/www.mdpi.com\/2227-9059\/10\/8\/1853\" target=\"_blank\" rel=\"noreferrer noopener\">10.3390\/biomedicines10081853<\/a>.<\/p>\n\n<p>Tesoro C, Ciriello R, Lelario F, Di Capua A, Pascale R, Bianco G, Dell\u2019Agli M, Piazza S, Guerrieri A, Scrano L, Bufo SA, Acquavia MA. Development and Validation of a Reversed-Phase HPLC Method with UV Detection for the Determination of L-Dopa in <em>Vicia faba<\/em> L. Broad Beans. <em>Molecules<\/em>. 2022; 27(21):7468. <a href=\"https:\/\/doi.org\/10.3390\/molecules27217468\" target=\"_blank\" rel=\"noreferrer noopener\">https:\/\/doi.org\/10.3390\/molecules27217468<\/a><\/p>\n\n<hr class=\"wp-block-separator has-alpha-channel-opacity is-style-wide\" \/>\n\n<h2 class=\"wp-block-heading\">2021<\/h2>\n\n<p>Barani M, Sangiovanni E, Angarano M, Rajizadeh MA, Mehrabani M, Piazza S, Gangadharappa HV, Pardakhty A, Mehrbani M, Dell\u2019Agli M, Nematollahi MH. Phytosomes as Innovative Delivery Systems for Phytochemicals: A Comprehensive Review of Literature. <em>Int J Nanomedicine<\/em>. 2021;16:6983-7022 <a href=\"https:\/\/doi.org\/10.2147\/IJN.S318416\">https:\/\/doi.org\/10.2147\/IJN.S318416<\/a><\/p>\n\n<p>Di Cesare Mannelli L, Palma Esposito F, Sangiovanni E, Pagano E, Mannucci C, Polini B, Ghelardini C, Dell\u2019Agli M, Izzo AA, Calapai G, de Pascale D, Nieri P. Pharmacological Activities of Extracts and Compounds Isolated from Mediterranean Sponge Sources. <em>Pharmaceuticals<\/em>. 2021; 14(12):1329. <a href=\"https:\/\/doi.org\/10.3390\/ph14121329\" target=\"_blank\" rel=\"noreferrer noopener\">https:\/\/doi.org\/10.3390\/ph14121329<\/a><\/p>\n\n<p>Magnavacca A, Piazza S, Cammisa A, Fumagalli M, Martinelli G, Giavarini F, Sangiovanni E, Dell\u2019Agli M. <em>Ribes nigrum<\/em> Leaf Extract Preferentially Inhibits IFN-\u03b3-Mediated Inflammation in HaCaT Keratinocytes. <em>Molecules<\/em>. 2021; 26(10):3044. <a href=\"https:\/\/doi.org\/10.3390\/molecules26103044\" target=\"_blank\" rel=\"noreferrer noopener\">https:\/\/doi.org\/10.3390\/molecules26103044<\/a><\/p>\n\n<p>Donatella Canistro, Annalisa Chiavaroli, Donatella Cicia, Francesco Cimino, Diego Curr\u00f2, Mario Dell\u2019Agli, Claudio Ferrante, Lisa Giovannelli, Sheila Leone, Giulia Martinelli, Luigi Milella, Ester Pagano, Stefano Piazza, Maria Ponticelli, Lucia Recinella, Sara Ristori, Enrico Sangiovanni, Antonella Smeriglio, Antonio Speciale, Domenico Trombetta, Fabio Vivarelli. The pharmacological basis of the curcumin nutraceutical uses: an update. <em>Pharmadvances<\/em>. 3 (2), June 2021 <a href=\"http:\/\/dx.doi.org\/10.36118\/pharmadvances.2021.06\" target=\"_blank\" rel=\"noreferrer noopener\">http:\/\/dx.doi.org\/10.36118\/pharmadvances.2021.06<\/a><\/p>\n\n<p>Atchan Nwakiban AP, Passarelli A, Da Dalt L, Olivieri C, Demirci TN, Piazza S, Sangiovanni E, Carpentier-Maguire E, Martinelli G, Shivashankara ST, Manjappara UV, Tchamgoue AD, Agbor GA, Kuiate JR, Daglia M, Dell&#8217;Agli M, Magni P. Cameroonian Spice Extracts Modulate Molecular Mechanisms Relevant to Cardiometabolic Diseases in SW 872 Human Liposarcoma Cells. Nutrients. 2021 Nov 26;13(12):4271. doi: <a href=\"https:\/\/www.mdpi.com\/2072-6643\/13\/12\/4271\" target=\"_blank\" rel=\"noreferrer noopener\">10.3390\/nu13124271<\/a>.<\/p>\n\n<p>Melzi G, Marabini L, Marinovich M, Dell&#8217;Agli M, Piazza S, Lombardo G, Donetti E. Photoprotective properties of Vitis vinifera L. leaves extract on UVA-induced damage in human endothelial cells (EA.hy926 cells). Photodermatol Photoimmunol Photomed. 2021 Mar;37(2):171-174. doi: <a href=\"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/phpp.12628\" target=\"_blank\" rel=\"noreferrer noopener\">10.1111\/phpp.12628.<\/a> <\/p>\n\n<p>Sangiovanni E, Dell&#8217;Agli M. Special Issue: Anti-Inflammatory Activity of Plant Polyphenols 2.0. Biomedicines. 2021 Dec 24;10(1):37. doi: <a href=\"https:\/\/www.mdpi.com\/2227-9059\/10\/1\/37\" target=\"_blank\" rel=\"noreferrer noopener\">10.3390\/biomedicines10010037<\/a>. <\/p>\n\n<p>M\u00e9ndez D, Escalona-Arranz JC, Foubert K, Matheeussen A, Van der Auwera A, Piazza S, Cuypers A, Cos P, Pieters L. Chemical and Pharmacological Potential of <em>Coccoloba cowellii<\/em>, an Endemic Endangered Plant from Cuba. <em>Molecules<\/em>. 2021 Feb 10;26(4):935. doi: <a href=\"https:\/\/www.mdpi.com\/1420-3049\/26\/4\/935\" target=\"_blank\" rel=\"noreferrer noopener\">10.3390\/molecules26040935<\/a>. <\/p>\n\n<hr class=\"wp-block-separator has-alpha-channel-opacity is-style-wide\" \/>\n\n<h2 class=\"wp-block-heading\">2020<\/h2>\n\n<p>Nwakiban APA, Fumagalli M, Piazza S, Magnavacca A, Martinelli G, Beretta G, Magni P, Tchamgoue AD, Agbor GA, Kuiat\u00e9 J-R, Dell\u2019Agli M, Sangiovanni E. Dietary Cameroonian Plants Exhibit Anti-Inflammatory Activity in Human Gastric Epithelial Cells. <em>Nutrients<\/em>. 2020; 12(12):3787. <a href=\"https:\/\/doi.org\/10.3390\/nu12123787\" target=\"_blank\" rel=\"noreferrer noopener\">https:\/\/doi.org\/10.3390\/nu12123787<\/a><\/p>\n\n<p>Sbrini G, Brivio P, Sangiovanni E, Fumagalli M, Racagni G, Dell\u2019Agli M, Calabrese F. Chronic Treatment with a Phytosomal Preparation Containing <em>Centella asiatica<\/em> L. and <em>Curcuma longa<\/em> L. Affects Local Protein Synthesis by Modulating the BDNF-mTOR-S6 Pathway. <em>Biomedicines<\/em>. 2020; 8(12):544. <a href=\"https:\/\/doi.org\/10.3390\/biomedicines8120544\" target=\"_blank\" rel=\"noreferrer noopener\">https:\/\/doi.org\/10.3390\/biomedicines8120544<\/a><\/p>\n\n<p>Piazza S, Fumagalli M, Khalilpour S, Martinelli G, Magnavacca A, Dell\u2019Agli M, Sangiovanni E. A Review of the Potential Benefits of Plants Producing Berries in Skin Disorders. <em>Antioxidants<\/em>. 2020; 9(6):542. <a href=\"https:\/\/doi.org\/10.3390\/antiox9060542\" target=\"_blank\" rel=\"noreferrer noopener\">https:\/\/doi.org\/10.3390\/antiox9060542<\/a><\/p>\n\n<p>Nozza E, Melzi G, Marabini L, Marinovich M, Piazza S, Khalilpour S, Dell\u2019Agli M, Sangiovanni E. <em>Rhus coriaria<\/em> L. Fruit Extract Prevents UV-A-Induced Genotoxicity and Oxidative Injury in Human Microvascular Endothelial Cells. <em>Antioxidants<\/em>. 2020; 9(4):292. <a href=\"https:\/\/doi.org\/10.3390\/antiox9040292\" target=\"_blank\" rel=\"noreferrer noopener\">https:\/\/doi.org\/10.3390\/antiox9040292<\/a><\/p>\n\n<p>Marabini L, Melzi G, Lolli F, Dell&#8217;Agli M, Piazza S, Sangiovanni E, Marinovich M. Effects of Vitis vinifera L. leaves extract on UV radiation damage in human keratinocytes (HaCaT). J Photochem Photobiol B. 2020 Mar;204:111810. doi: <a href=\"https:\/\/www.sciencedirect.com\/science\/article\/abs\/pii\/S1011134419307870?via%3Dihub\" target=\"_blank\" rel=\"noreferrer noopener\">10.1016\/j.jphotobiol.2020.111810.<\/a><\/p>\n\n<p>Sbrini G, Brivio P, Fumagalli M, Giavarini F, Caruso D, Racagni G, Dell&#8217;Agli M, Sangiovanni E, Calabrese F. <em>Centella asiatica<\/em> L. Phytosome Improves Cognitive Performance by Promoting Bdnf Expression in Rat Prefrontal Cortex. Nutrients. 2020 Jan 29;12(2):355. doi: <a href=\"https:\/\/www.mdpi.com\/2072-6643\/12\/2\/355\" target=\"_blank\" rel=\"noreferrer noopener\">10.3390\/nu12020355.<\/a><\/p>\n\n<p>Nwakiban APA, Cicolari S, Piazza S, Gelmini F, Sangiovanni E, Martinelli G, Bossi L, Carpentier-Maguire E, Tchamgoue AD, Agbor G, Kuiat\u00e9 JR, Beretta G, Dell&#8217;Agli M, Magni P. Oxidative Stress Modulation by Cameroonian Spice Extracts in HepG2 Cells: Involvement of Nrf2 and Improvement of Glucose Uptake. Metabolites. 2020 May 1;10(5):182. doi: <a href=\"https:\/\/www.mdpi.com\/2218-1989\/10\/5\/182\" target=\"_blank\" rel=\"noreferrer noopener\">10.3390\/metabo10050182.<\/a><\/p>\n\n<p>Galimberti A, Cena H, Campone L, Ferri E, Dell&#8217;Agli M, Sangiovanni E, Belingheri M, Riva MA, Casiraghi M, Labra M. Rethinking Urban and Food Policies to Improve Citizens Safety After COVID-19 Pandemic. Front Nutr. 2020 Oct 8;7:569542. doi: <a href=\"https:\/\/www.frontiersin.org\/articles\/10.3389\/fnut.2020.569542\/full\" target=\"_blank\" rel=\"noreferrer noopener\">10.3389\/fnut.2020.569542.<\/a> <\/p>\n\n<p>Berenguer-Rivas CA, Escalona-Arranz JC, Llaurad\u00f3-Maury G, Van der Auwera A, Piazza S, M\u00e9ndez-Rodr\u00edguez D, Foubert K, Cos P, Pieters L. Anti-inflammatory effect of <em>Adelia ricinella<\/em> L. aerial parts. <em>J Pharm Pharmacol.<\/em> 2021 Mar 8;73(4):553-559. doi: <a href=\"https:\/\/academic.oup.com\/jpp\/article\/73\/4\/553\/6102455?login=false\">10.1093\/jpp\/rgaa057<\/a><\/p>\n\n<hr class=\"wp-block-separator has-alpha-channel-opacity is-style-wide\" \/>\n\n<h2 class=\"wp-block-heading\">2019<\/h2>\n\n<p>Khalilpour S, Sangiovanni E, Piazza S, Fumagalli M, Beretta G, Dell&#8217;Agli M. <em>In vitro<\/em> evidences of the traditional use of <em>Rhus coriaria<\/em> L. fruits against skin inflammatory conditions. <em>J Ethnopharmacol.<\/em> 2019 Jun 28;238:111829. <a href=\"https:\/\/doi.org\/10.1016\/j.jep.2019.111829\" target=\"_blank\" rel=\"noreferrer noopener\">https:\/\/doi.org\/10.1016\/j.jep.2019.111829<\/a><\/p>\n\n<p>Piazza S, Pacchetti B, Fumagalli M, Bonacina F, Dell&#8217;Agli M, Sangiovanni E. Comparison of Two <em>Ginkgo biloba<\/em> L. Extracts on Oxidative Stress and Inflammation Markers in Human Endothelial Cells. <em>Mediators Inflamm<\/em>. 2019 Jun 25;2019:6173893. <a href=\"https:\/\/doi.org\/10.1155\/2019\/6173893\" target=\"_blank\" rel=\"noreferrer noopener\">https:\/\/doi.org\/10.1155\/2019\/6173893<\/a><\/p>\n\n<p>Sangiovanni E, Fumagalli M, Pacchetti B, Piazza S, Magnavacca A, Khalilpour S, Melzi G, Martinelli G, Dell&#8217;Agli M. <em>Cannabis sativa<\/em> L. extract and cannabidiol inhibit in vitro mediators of skin inflammation and wound injury. <em>Phytother Res.<\/em> 2019 Aug;33(8):2083-2093. <a href=\"https:\/\/doi.org\/10.1002\/ptr.640\" target=\"_blank\" rel=\"noreferrer noopener\">https:\/\/doi.org\/10.1002\/ptr.6400<\/a><\/p>\n\n<p>Sangiovanni E, Fumagalli M, Santagostini L, Forino M, Piazza S, Colombo E, Taglialatela-Scafati O, Fico G, Dell&#8217;Agli M. (2019). A bio-guided assessment of the anti-inflammatory activity of hop extracts (<em>Humulus lupulus<\/em> L. cv. Cascade) in human gastric epithelial cells. <em>Journal of Functional Foods.<\/em>  57. 95-<a href=\"https:\/\/doi.org\/10.1016\/j.jff.2019.03.041\">https:\/\/doi.org\/10.1016\/j.jff.2019.03.041<\/a><\/p>\n\n<p>Sangiovanni E, Di Lorenzo C, Piazza S, Manzoni Y, Brunelli C, Fumagalli M, Magnavacca A, Martinelli G, Colombo F, Casiraghi A, Melzi G, Marabini L, Restani P, Dell\u2019Agli M. <em>Vitis vinifera<\/em> L. Leaf Extract Inhibits In Vitro Mediators of Inflammation and Oxidative Stress Involved in Inflammatory-Based Skin Diseases. <em>Antioxidants<\/em>. 2019; 8(5):134. <a href=\"https:\/\/doi.org\/10.3390\/antiox8050134\" target=\"_blank\" rel=\"noreferrer noopener\">https:\/\/doi.org\/10.3390\/antiox8050134<\/a><\/p>\n\n<p>Colombo F, Di Lorenzo C, Regazzoni L, Fumagalli M, Sangiovanni E, Peres de Sousa L, Bavaresco L, Tomasi D, Bosso A, Aldini G, Restani P, Dell&#8217;Agli M. Phenolic profiles and anti-inflammatory activities of sixteen table grape (<em>Vitis vinifera<\/em> L.) varieties. <em>Food Funct<\/em>. 2019 Apr 17;10(4):1797-1807. <a href=\"https:\/\/doi.org\/10.1039\/C8FO02175A\">https:\/\/doi.org\/10.1039\/C8FO02175A<\/a><\/p>\n\n<p>D&#8217;Alessandro S, Magnavacca A, Perego F, Fumagalli M, Sangiovanni E, Prato M, Dell&#8217;Agli M, Basilico N. Effect of Hypoxia on Gene Expression in Cell Populations Involved in Wound Healing. Biomed Res Int. 2019 Aug 22;2019:2626374. doi: <a href=\"https:\/\/doi.org\/10.1155\/2019\/2626374\" target=\"_blank\" rel=\"noreferrer noopener\">10.1155\/2019\/2626374.<\/a> <\/p>\n\n<p>Franco AM, Tocci N, Guella G, Dell&#8217;Agli M, Sangiovanni E, Perenzoni D, Vrhovsek U, Mattivi F, Manca G. Myrtle Seeds (<em>Myrtus communis<\/em> L.) as a Rich Source of the Bioactive Ellagitannins Oenothein B and Eugeniflorin D<sub>2<\/sub>. ACS Omega. 2019 Sep 20;4(14):15966-15974. doi: <a href=\"https:\/\/doi.org\/10.1021\/acsomega.9b02010\" target=\"_blank\" rel=\"noreferrer noopener\">10.1021\/acsomega.9b02010.<\/a><\/p>\n\n<p>Atchan Nwakiban AP , Sokeng AJ , Dell&#8217;Agli M , Bossi L , Beretta G , Gelmini F , Deutou Tchamgoue A , Agbor Agbor G , Kuiat\u00e9 JR , Daglia M , Magni P . Hydroethanolic plant extracts from Cameroon positively modulate enzymes relevant to carbohydrate\/lipid digestion and cardio-metabolic diseases. Food Funct. 2019 Oct 16;10(10):6533-6542. doi: <a href=\"https:\/\/doi.org\/10.1039\/C9FO01664C\" target=\"_blank\" rel=\"noreferrer noopener\">10.1039\/c9fo01664c.<\/a><\/p>\n\n<p><\/p>\n","protected":false},"excerpt":{"rendered":"<p>2025 Martinelli G, Maranta N, Nicotra G, Vicentini SF, Bruno B, Baron G, Di Lorenzo C, Moheb El Haddad S, Fumagalli M, Pozzoli C, Sangiovanni E, Aldini G, Dell\u2019Agli M, Piazza S. Cistus x incanus L. extract as a complex polyphenolic blend with retained anti-adhesive and anti-inflammatory properties in a model of E. coli-induced UTI [&hellip;]<\/p>\n","protected":false},"author":4,"featured_media":616,"parent":0,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"_acf_changed":false,"footnotes":""},"class_list":["post-1037","page","type-page","status-publish","has-post-thumbnail","hentry"],"acf":[],"_links":{"self":[{"href":"https:\/\/farmacognosia.unimi.it\/en\/wp-json\/wp\/v2\/pages\/1037"}],"collection":[{"href":"https:\/\/farmacognosia.unimi.it\/en\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/farmacognosia.unimi.it\/en\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/farmacognosia.unimi.it\/en\/wp-json\/wp\/v2\/users\/4"}],"replies":[{"embeddable":true,"href":"https:\/\/farmacognosia.unimi.it\/en\/wp-json\/wp\/v2\/comments?post=1037"}],"version-history":[{"count":20,"href":"https:\/\/farmacognosia.unimi.it\/en\/wp-json\/wp\/v2\/pages\/1037\/revisions"}],"predecessor-version":[{"id":2289,"href":"https:\/\/farmacognosia.unimi.it\/en\/wp-json\/wp\/v2\/pages\/1037\/revisions\/2289"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/farmacognosia.unimi.it\/en\/wp-json\/wp\/v2\/media\/616"}],"wp:attachment":[{"href":"https:\/\/farmacognosia.unimi.it\/en\/wp-json\/wp\/v2\/media?parent=1037"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}